What is Fat Transfer?

Fat Transfer by Nutational Infrasonsice Liposculpure (N.I.L.) is a simple, fast, gentle, and low cost fat harvesting/transfer method, which yields quality reinjectable adipose tissue with high potency of adipose derived regenerative cells (ADRC’s).

The low frequency “non heat” INFRASONIC vibration enables the removal of body fat while protecting the surrounding tissues, resulting in smooth contour and a rapid recovery. This process is a proven, reliable system that safely enables precise, high volume de-bulking in all body areas. The NUTATIONAL pattern offers notable benefits, especially in the areas of fibrosis (secondary liposuction, backs, and in males).

Infrasonic vibration during the infiltration and operative fat emulsification creates many benefits. Vibration interferes with the conduction of painful stimuli by activating nerves that do not transmit pain signals. This advantage allows physicians to perform the liposuction procedure under local or IV sedation with the likelihood of increased patient comfort.
 

Clinical Results


Clinical studies have shown N.I.L. yields

  • "Superior" volume of adipose derived regenerative cells (ADRC’s) compared to standard liposuction1
  • Twice the volume of ADRC’s and three times the volume of mesenchymal cells2
  • Highly viable cells1 2

1Baptista, et al., An alternative method for the isolation of mesenchymal stromal cells derived from lipoaspirate samples, Cytotherapy (2009) Vol. II, No. 6, 706-715.
2 Angeloni, Nutational Infrasonic Liposculpture (NIL) Adipose Derive Regenerative Cell Concentration and Viability Study Summary, non-published November 2011.

 

The Technology

N.I.L. uses compressed air in order to drive the tip of the cannula into a 3-dimensional precession movement called the nutation.

Infrasound (low frequency: lower than 20hz) isgenerated by the nutational mode of action. This “nutational infrasonic effect” produced during N.I.L. is believed to be the key to causing the in vivo dissociation of large numbers of regenerative cells from connective tissues and resident vasculature.

Finally, gentle suction removes the lipoaspirate, which includes small fat clusters and a large population of free floating a ARC’s in mixture of tumescent fluid.

 

 

The Process

The Fat Transfer protocol suggests the use of a special harvesting cannula (patent pending), which gently removes small adipose cell clusters, which have been loosened inside the body via the patented "nutational infrasonic effect" produced by the N.I.L. system.

Fat, which is rich in regenerative cells, is collected into a sterile decanting container. After a brief settling period, excess tumescent fluid is drained, then remaining fat cells are drawn into re-injection syringes for immediate autologous transplantation.

The result is high quality, viable fat for use in natural breast augmentations, Brazilian butt lifts, and transfer to hands and face.

Recent studies have shown that decanting is preferable to centrifugation for fat survivability. Centrifugation tends to damage fragile cells and has also been shown to deplete the separated fat of beneficial ADRC’s1. The Fat Transfer protocol suggests that sterile decantation will preserve the integrity of fat cells and retain the rich volume of free-floating ADRC's.

1Conde-Green, Influence of decantation, washing and centrifugation on adipocyte and mesenchymal stem cell content of aspirated adipose tissue: A comparative study. Journal of Plastic, Reconstructive & Aesthetic Surgery, Vol 63, No. 8, 1375-1381 (Aug 2010)
 

 

Stem Cell Content Influences Outcome

Studies have shown that a high population of ADRC’s present within transplanted fat cells will increase survival rates and volume retention, due to enhanced angiogenesis and adipose cell replacement.1

The high yield of ADRC’s resulting from the in vivo dissociation of regenerative cells makes fat harvested using the Fat Transfer protocol an ideal re-injectable material for achieving predictable outcomes.

1Yoshimura, et. al, Cell-assisted lipotransfer for cosmetic breast augmentation: Supportive use of adipose-derived stem/stromal cells. Aesthetic Plastic Surgery (2008) 32:48-55

 

 

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